Evaluation of nasal oxytocin spray efficacy in scales of the withdrawal sign and craving and relapse When cutting methadone in opioids addicted people that have received methadone .

Tehran University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2019年12月17日

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•These people are all men.
•They are between 18 and 55 years old.
•They have a history of drug addiction, with the drug being discontinued and replaced with methadone.
•The amount of methadone consumed is between 10 and 100 mg
•They have been on methadone maintenance therapy for longer than 6 months
•now on his own offer Or, as the need arises (example with travel abroad, employment or marriage)he wants to cut off methadone consumption.
•But despite the high tendency to Interruption of methadone has not been able to reduce methadone levels
•in 14 days Recently, his methadone dose has not changed.
•This pations were no positive morphine test for the past 3 months.

•There is a history of seizures
•Recent history of brain injury
•drug abuse in the past 3 months
•Severe suicidal thoughts with severe depression
•Severe allergic disease
•Severe neurological disorders, especially if it causes increased risk of seizure
•Acute cardiac abnormalities present
•History of psychotic disorders
•acute vascular disorders

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