临床试验/NCT00000301

NCT00000301已完成2 期

Rapid Evaluation of Cocaine Pharmacotherapies (Amantadine)

University of California, Los Angeles2 个研究点分布在 1 个国家开始时间: 1996年3月1日最近更新: 2016年7月11日

适应症

试验速览

阶段: 2 期
状态: 已完成
发起方: University of California, Los Angeles
试验地点: 2
主要终点: Cocaine craving

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to empirically test a series of medications to: 1) determine each medication's efficacy in treatment of cocaine abuse/dependence; 2) find most effective dose range for each medication. In this study, amantadine is tested."

详细描述

16-week participation plus a 2 weekk lead-in period. Participants are assigned randomly to placebo or amantadine. Participants attend group meeting 3 times/week

研究设计

研究类型: Interventional
分配方式: Randomized
主要目的: Treatment
盲法: Double

入排标准

年龄范围: 18 Years 至 65 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•M/F, ages 18-
•cocaine dependence according to DMS-IV criteria. Self-reported use within the last 30 days. Agreeable to conditions of the study and signed informed consent.

排除标准

•Psychiatric disorder that requires medication therapy, history of seizures. Pregnant and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative-hypnotics. Acute hepatitis. Other medical conditions that deem participation to be unsafe.

结局指标

主要结局

Cocaine craving

Retention

Psychosocial progress

Cocaine use

次要结局

未报告次要终点

研究者

发起方

University of California, Los Angeles

申办方类型

Other

研究点 (2)

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