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临床试验/NCT07465419
NCT07465419已完成不适用

Evaluation of the Effect of Internal Jugular Vein Catheterization on Intracranial Pressure Using Optic Nerve Sheath Diameter in Intubated Patients in the Intensive Care Unit

Cumhuriyet University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2026年2月1日最近更新:
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
50
试验地点
1
主要终点
Optic nerve sheath diameter

研究概览

简要总结

The aim of this study is to evaluate the effect of internal jugular vein catheterization on intracranial pressure in intubated patients in the intensive care unit using optic nerve sheath diameter

详细描述

Before central venous catheter insertion, the baseline ONSD value will be determined by measuring the optic nerve sheath diameter in the supine and Trendelenburg positions (15 degrees head down).

Immediately after central venous catheter insertion, the measurement will be taken while the patient is still in the Trendelenburg position. The measurement will be repeated at 5, 15, and 30 minutes after the patient is placed in the supine position.

Transorbital optic nerve sheath diameter measurements will be performed using the linear probe of the ultrasound device routinely used in our clinic. The ultrasound linear probe will be gently placed on the eyelid over the closed eye, ensuring no pressure is applied to the patient's eye. The length of the line representing the optic nerve sheath diameter, which intersects the line drawn 3 mm downwards from the lower edge of the eyeball seen on the ultrasound, will be measured and recorded. The optic nerve sheath diameter will be measured transorbitally vertically once from each eye during the first measurement, and the average will be taken.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • The study will include adult patients over 18 years of age who are on mechanical ventilation support and monitored in the intensive care unit.

排除标准

  • patients with intracranial tumors
  • patients with acute traumatic brain injury
  • patients diagnosed with acute or chronic eye diseases
  • hypercarbic patients
  • Patients receiving inotropic support
  • patients using medications that affect intraocular pressure

研究组 & 干预措施

IJV catheterization in ICU

Intubated patients in intensive care unit who receive internal jugular vein catheterization

干预措施: Internal jugular vein catheterization (Procedure)

结局指标

主要结局

Optic nerve sheath diameter

时间窗: Prior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterization

Optic nerve sheath diameter will be measured via ultrasound prior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterization

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Oguz Gundogdu

Associate Professor

Cumhuriyet University

研究点 (1)

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