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临床试验/CTRI/2026/01/101669
CTRI/2026/01/101669尚未招募不适用

Comparative study of efficacy of 5% lignocaine patch for post-operative analgesia in cardiac surgical patients: A cross-sectional controlled trial

MGM Medical College and Hospital1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2026年2月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
70
试验地点
1

研究概览

简要总结

Post-sternotomy pain remains a significant clinical challenge in cardiac

surgery, often requiring substantial analgesic requirement in the immediate

postoperative period. While opioids are effective analgesics, their adverse

effect profile; including respiratory depression, sedation, gastrointestinal

dysfunction, and risk of long-term dependence; underscores the urgent need

for opioid-sparing strategies.

Topical lidocaine in the form of a 5% transdermal patch offers a non-invasive, low-

risk intervention that provides localized analgesia with minimal systemic

absorption. Although lidocaine patches have demonstrated efficacy in treating

neuropathic and localized pain conditions, their role in the management of acute

post-sternotomy pain remains underexplored.

This study proposes to evaluate the efficacy of the 5% lidocaine patch in reducing

post-sternotomy pain and opioid requirements within the first 24 hours following

cardiac surgery. By addressing a key gap in postoperative pain management, this

research has the potential to inform enhanced recovery pathways, reduce opioid

exposure, and improve patient outcomes in a high-risk population

研究设计

研究类型
Observational

入排标准

年龄范围
20.00 Year(s) 至 75.00 Year(s)(—)
性别
All

入选标准

  • Patients giving consent for procedures 2) Patients in the age group of 20-75 years 3) Patients scheduled to undergo cardiac surgery through a full median sternotomy approach.

排除标准

  • Known hypersensitivity or allergic reaction to lignocaine patches.
  • Current use of Class I antiarrhythmic medications, such as lignocaine, tocainide, procainamide, mexiletine, or propafenone.
  • Preoperative use of medications for acute or chronic pain conditions, including non-steroidal anti-inflammatory drugs (NSAIDs), tramadol, opioids, antidepressants, or anticonvulsants.

研究者

申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Jaslin Biswajit Acharya

MGM Medical College and Hospital

研究点 (1)

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