Vpliv COVID19 na Izgubo Funkcionalnih zmožnosti Pacientov po zaključenem bolnišničnem Zdravljenju The Effect of COVID19 on the Loss of Functional Capacity of Patients After Hospitalization
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- Pulse wave velocity (PWV)
研究概览
简要总结
The main objective of the proposed study is to evaluate the impact of coronavirus (2019-nCoV), hereafter COVID -19, on patients' loss of functional capacity after completion of hospital treatment. Specifically, the research will focus on examining changes in musculoskeletal, cardiovascular, and respiratory function, as well as motor control. In addition, we aim to evaluate rehabilitation treatments after recovery from COVID -19 and consider additional preventive measures based on previous experience.
详细描述
The combination of such a severe respiratory disease as COVID -19 with motor inactivity could have very serious consequences for a person's general health even after COVID -19 symptoms have subsided. To date, the effects of COVID -19 on individual muscle status have not been extensively studied. Therefore, the main objective of this study will be to evaluate the muscle status of patients after COVID -19. In addition, we will be interested in longitudinal monitoring of individuals' rehabilitation, where they will receive instructions based on measured outcomes at hospital discharge. We will also be interested in considering additional preventive measures for future patients based on previous experience of infected and hospitalized COVID -19 patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Completed hospital treatment after a positive COVID-19 test
- •Signed written consent
排除标准
- •Still testing positive for COVID -19 at discharge.
- •Severe musculoskeletal injuries (e.g., disability).
- •Inability to follow instructions when performing the test.
结局指标
主要结局
Pulse wave velocity (PWV)
时间窗: Change in PWV between both assessment points (pre- to 2 months post-measurement)
Measuring endothelium function in supine
Spirometry
时间窗: Change in FVC (%) between both assessment points (pre- to 2 months post-measurement)
Measurement of lung function, specifically the forced vital capacity (FVC)
Timed up and go test (TUG)
时间窗: Change in time on TUG between both assessment points (pre- to 2 months post-measurement)
Functional performance of the patients from sitting to standing, walking and turning
次要结局
- Trail making test B(Change in time to solve the TMT B test between both assessment points (pre- to 2 months post-measurement))
- Walking velocity(Change in gait velocity between both assessment points (pre- to 2 months post-measurement))