In older people with sarcopenia, does protein supplementation, compared to isocaloric placebo or no supplementation, maintain or improve physical performance

niversity of Helsinki0 个研究点目标入组 250 人开始时间: 2012年11月28日最近更新: 2020年1月13日

试验速览

暂无简介。

•75 years or older, living permanently at home in Porvoo, Finland
•low hand grip strength (men < 30.0 kg, women < 20.0 kg) or slow habitual gait speed (< 0,80 m/s)
•low skeletal muscle index (2 standard deviations below young adults) measured by direct segmental calf bioimpedance spectroscopy.
•voluntary participation, written informed consent to participate in study by participant or her/his closest proxy.

•not living at home
•not able to walk indoors independently (canes and walkers allowed)
•not able to co-operate with hand grip, walking speed, and bioimpedance measurements
•plasma creatinine > 150 µmol/l
•terminal illness (estimated prognosis > 6 months)
•cardiac pacemaker
•bilateral replacement arthroplasty of the knee
•severe skin lesions in bioimpedance electrode placement sites (dorsal foot, dorsal ankle, lateral knee, dorsal wrist, and dorsal palm)

发起方

niversity of Helsinki