NCT02156362Unknown不适用
Determination of Pronostics Factors for Advanced Thyroid Carcinoma (pT3 pT4 or M1 at Diagnosis)
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 643
- 试验地点
- 2
- 主要终点
- Rate of Thyroid cancer evolving to refractory stage
研究概览
简要总结
It is generally estimated that 5 % of patients with thyroid cancer will develop distant metastases, and most of them had an advanced stage of the disease at presentation. Thirty per cent of them are resistant to radio iodine therapy and are called "refractory". Their long term survival is estimated to be less than 10 %.
The objective of this study is to identify the factors associated with poor outcome in a cohort of patients with advanced thyroid cancer followed during 5 years. Anaplastic and medullary thyroid carcinomas were excluded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Man or woman ≥ 18 years.
- •Thyroid cancer differentiated from follicular origins (papillary, vesicular or poorly differentiated carcinoma).
- •TNM classification: stage pT3 (≥2 cm), or pT4 or M1 at diagnosis.
- •Patient after post operative radioiodine therapy.
排除标准
- •Patient who can not be followed during the protocol.
- •Patient who does not consent.
结局指标
主要结局
Rate of Thyroid cancer evolving to refractory stage
时间窗: 5 years
次要结局
未报告次要终点
研究者
研究点 (2)
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