NL-OMON51635招募中2 期
Prospective clinical trial to evaluate the efficacy of acetazolamide for the treatment of cystoid macular edema in inherited retinal dystrophies: the CAR trial - The CAR trial
Amsterdam UMC0 个研究点目标入组 18 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 18
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 12 至 99（—）
入选标准
- •Eligible patients received a clinical diagnosis of IRD, and underwent at least
- •one clinical examination, in combination with one of the following
- •prerequisites:
- •IRD associated with causal genetic variant(s) (in e.g., USH2A, CRB1, RHO,
- •RP1, RP2, RPGR, PRPF31, or RS1 gene)
- •CME involving the fovea confirmed on spectral-domain optical coherence
- •tomography (OCT)
排除标准
- •A potential subject who meets any of the following criteria will be excluded
- •from participation in this study:
- •Eyes will be excluded when the visual dysfunction is also significantly
- •associated with other ocular diseases besides the IRDs (e.g., glaucoma,
- •perforating trauma).
- •Patients treated with loop diuretics
- •Severe hepatic impairment
- •Severe renal insufficiency
- •Sodium and Potassium Depletion
- •Addison's disease
- •Hyperchloremic Acidosis
- •Cor pulmonale
- •Chronic non-congestive angle-closure glaucoma
- •The use of Acetazolamide
- •• Patients treated with interacting medication such as:
- •o Folic acid antagonists: methotrexate, trimethoprim and pyrimethamine
- •o Hypoglycaemics
- •o Oral anti-coagulants
- •o Cardiac glycosides: digoxine
- •o diuretics, such as thiazides and loop diuretics:
- •o anticonvulsants such as: phenytoin, primidone and carbamazepine
- •o Carbonic Anhydrase Inhibitors
- •o Sodium hydrogen carbonate
- •o Cyclosporine
- •o Ephedrine, methadone, amphetamine, quinidine and lithium
研究者
相似试验
招募中
不适用
Prospective clinical study to evaluate efficacy of ICOLENS TM, a bifocal corneal implant to treat presbyopiaH52.4PresbyopiaDRKS00000459eoptics AG30
招募中
Unknown
Prospective Clinical Trial for Evaluation of Efficacy of AI Assistant System in Breast Cancer ScreeningNeoplasmsKCT0009007ational Cancer Center3,057
进行中（未招募）
不适用
Clinical prospective study to evaluate the efficacy of hygienical therapy and metronidazole in addition to antibiotic therapy in patients affected by bisphosponate-associated osteonecrosis of the jaws - CH.MAX-FACC.02/2009EUCTR2010-019060-37-ITAZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
进行中（未招募）
Unknown
Testing a food supplement for reducing stress on studentsStressMental and Behavioural DisordersISRCTN14084189ROELMI HPC Srl42
招募中
不适用
The clinical trial to examine the efficacy of the intravitreal injection of anti-VEGF antibody Bevacizumab(Avastin) for severe retinopathy of prematurity.Retinopathy of prematurityJPRN-UMIN000018069Gunma University Hospital Department of Ophthalmology4