NCT00782782Unknown不适用
Effect of Medications on Vascular Response in Patients With CHF and in Healthy Subjects
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- vascular sensitivity (ED50) and response (Emax) to dexmedetomidine, phenylephrine, isoproterenol and terbutaline
研究概览
简要总结
Congestive Heart failure (CHF) is asociated with changes in cardiac function and vascular responses. The aim of this study is to characterize these differences. Our hypothesis is, that there are differences in vascular responses between healthy subjects and patients with CHF.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with congestive heart failure NYHA I-II
- •Stable clinical condition
排除标准
- •Resting systolic blood pressure < 100
- •Resting heart rate < 50
- •Hypersensitivity to dexmedetomidine, phenylephrine, isoproterenol, terbutaline
结局指标
主要结局
vascular sensitivity (ED50) and response (Emax) to dexmedetomidine, phenylephrine, isoproterenol and terbutaline
时间窗: 3 weeks
次要结局
未报告次要终点
研究者
研究点 (1)
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