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临床试验/NCT04868864
NCT04868864Unknown不适用

The Ontario Multi-Regional Hospital COVID-19 Registry (COREG)- Recovery Trajectory Sub-study

Hamilton Health Sciences Corporation1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2021年5月15日最近更新:
适应症

试验速览

阶段
不适用
入组人数
200
试验地点
1
主要终点
Pulmonary changes on LDCT Scan

研究概览

简要总结

Radiological and lung function recovery following Covid-19 infection.

详细描述

The investigators propose to conduct pulmonary LDCT imaging and physiological lung function assessments, and combine this with detailed multi-regional hospitalization clinical data collection on COVID-19 cases (COREG registry); to inform long-term pulmonary and extra-pulmonary consequences and the recovery trajectory following COVID-19 infection.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients discharged from hospital post COVID-19 infection who have radiographic and clinical evidence of COVID-19 pneumonia during hospitalization.
  • Patients with evidence of unresolved radiographic changes or persistent hypoxemia.

排除标准

  • Failure to comply with study procedures.

结局指标

主要结局

Pulmonary changes on LDCT Scan

时间窗: Through study completion, an average of 9 months

Identify pulmonary changes utilizing LDCT chest to characterize the pulmonary recovery trajectory of survivors of COVID-19.

次要结局

  • DLCO(Through study completion, an average of 9 months)
  • TLC(Through study completion, an average of 9 months)
  • FEV1(Through study completion, an average of 9 months)
  • FVC(Through study completion, an average of 9 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

MyLinh Duong

Professor Department of Medicine

Hamilton Health Sciences Corporation

研究点 (1)

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