Quantitative assessment of myocardial perfusion with magnetic resonance using an intravascular contrast agent: an open label trial

King's College London (UK)0 个研究点目标入组 156 人开始时间: 2009年11月13日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Known coronary artery disease (with or without prior percutaneous revascularisation)
•2. Indication for percutaneous coronary intervention (PCI)
•3. The subject is 18 years of age or older, either sex
•4. The subject is conscious and able to comply with study procedures
•5. Written informed consent has been obtained

•1. Contraindications for magnetic resonance imaging (MRI)
•2. Contraindications to gadolinium-based contrast agents (known allergies or a contra-indication to gadolinium (Gd) chelates or renal insufficiency)
•3. Contraindications to adenosine stress:
•3.1. Myocardial infarction less than 3 days
•3.2. Unstable angina pectoris
•3.3. Severe arterial hypertension
•3.4. Asthma or severe obstructive pulmonary disease requiring treatment (chronic obstructive pulmonary disease [COPD])
•3.5. Sick sinus syndrome or a symptomatic bradycardia, atrioventricular (AV) block greater than IIa, trifascicular block
•3.6. Allergy against vasodilator
•3.7. Allergy against gadolinium-based contrast agents or renal insufficiency
•3.8. Other contraindications for adenosine or dipyridamole administration
•4. The subject has significant cardiac arrhythmia (i.e. atrial fibrillation)
•5. Pregnancy
•6. Heart failure (New York Heart Association [NYHA] grade IV)
•7. The subject's electrocardiogram (ECG) shows prolonged QT interval
•8. Severe arterial hypotension (less than 90 mmHg systolic)
•9. Claustrophobia

发起方

King's College London (UK)