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临床试验/NCT02650531
NCT02650531已完成不适用

Norwegian COgnitive Impairment After STroke (NorCOAST) Study

Norwegian University of Science and Technology1 个研究点 分布在 1 个国家目标入组 816 人开始时间: 2015年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
816
试验地点
1
主要终点
Score on the Montreal cognitive assessment (MOCA)

研究概览

简要总结

A prospective observational multicenter study aiming to describe incidence, and identify predictors for development of poststroke dementia (PSD) and mild cognitive impairment (MCI) after stroke

详细描述

About 15000 Norwegians suffer a stroke every year and 2/3 will be more or less disabled. In addition to motor impairments and comorbidities, disability after stroke is often related to post stroke dementia (PSD) or mild neurocognitive disorder (NCD). However, these problems are hardly addressed in stroke or dementia research and frequently ignored in clinical practise. In the Nor-COAST study an interdisciplinary research group will collaborate to establish a research platform across all Norwegian Health Authorities. The overall aim of the study is to improve competence on PSD and NCD in order to improve individual health outcomes following a stroke. The specific objectives are to determine the incidence of PSD and NCD and the consequences on function and use of health care services and to enhance the early detection of PSD and NCD by identifying a set of risk factors, ranging from genetics to physical activity. The incidence and impact of PSD and NCD on function and use of health care services, medication and life-style changes are important when planning future health care services. Tools identifying patients at risk might improve diagnostic work up and together with knowledge on pathogenic aspects it will contribute to future treatment and prevention of PSD and NCD.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Stroke diagnosis according to the WHO criteria

排除标准

  • Not scandinavian speaking

结局指标

主要结局

Score on the Montreal cognitive assessment (MOCA)

时间窗: 18 months

Performance based test

次要结局

  • Time spent in upright position(18 months)
  • Brain Imaging(18 months)
  • Selfreported habits concerning smoking, alcohol, diet and medication using standardised questionnaires(18 months)
  • Score on Short Physical Performance Battery (sppb)(18 months)
  • Score on the Montreal cognitive assessment (MOCA)(3 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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