CTRI/2020/10/028188尚未招募2 期
Role of Parecoxib, A Selective Cyclooxygenase-2 Inhibitor, for Reduction of Severity of Acute Pancreatitis: A Randomized Controlled Trial
Dr Pramod Kumar Garg0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Acute pancreatitis as defined by revised Atlanta classification.
- •2. The time interval from the onset of symptoms to presentation should be less than 7 days.
- •3. Systemic inflammatory response syndrome (SIRS) persisting for more than 24 hours.
排除标准
- •1. Age less than 18 years or more than 70 years
- •2. Patients with Grade 2 or more organ failure as per Modified Marshallâ??s criteria.
- •3. Patients with a serum creatinine >1.4 mg/dl
- •4. Active or past history of GI bleeding or peptic ulcer disease
- •5. Patients with significant co-morbidity such as coronary artery disease, chronic kidney disease, cirrhosis, chronic obstructive airway disease, inflammatory bowel disease, and congestive heart failure or malignancy.
- •6. Patients who have history of bronchospasm, urticaria, angioneurotic edema or other allergic reactions to COX-2 inhibitors
- •7. Patients with evidence of chronic pancreatitis
- •8. Pregnancy and breast feeding
- •9. Failure to give consent
研究者
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