A Comparative study of 0.5% hyperbaric Levobupivacaine and 0.5% hyperbaric Bupivacaine for spinal anaesthesia in elective lower segment casearean sections
试验速览
- 阶段
- Unknown
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare various effects of intrathecal 0.5% Hyperbaric Levobupivacaine & 0.5%hyperbaric Bupivacaine in elective lower segment casearean sections
研究概览
简要总结
Spinal anaesthesia is the most common anesthesia used in elective and emergency lower segment casearean sections.Hyperbaric solutions are generally preferred in subarachnoid block because they provide sufficient block and do not cause high block levels commonly
Bupivacaine has R and S enantiomers they have different affinity on sodium and potassium channels.S enantiomers are relatively less cardiotoxic and neurotoxic.In recent studies Levobupivacaine as safer alternative for regional anesthesia than racemic Bupivacaine.
Hence we aim to study hyperbaric Levobupivacaine 0.5%, and Hyperbaric Bupivacaine 0.5%, with respect to hemodynamic changes,block characteristics, postoperative complications
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.Patients undergoing elective lower segment casearean sections from 18-40years age 2.ASA physical status II.
排除标准
- •1.Patients with ASA physical status III,IV 2.Patients having any contraindications to spinal anaesthesia 3.Patients with history of allergy to local anaesthetic.
结局指标
主要结局
To compare various effects of intrathecal 0.5% Hyperbaric Levobupivacaine & 0.5%hyperbaric Bupivacaine in elective lower segment casearean sections
时间窗: At Oth minute immediately & then 3 6 9 15 20 25 30 45 60 75 90
1.Hemodynamic changes
时间窗: At Oth minute immediately & then 3 6 9 15 20 25 30 45 60 75 90
次要结局
- Sensory & motor blockade characteristics(At 5minutes)