Detection of Microplastics in Patients With Periodontitis - a Cross-sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 25
- 主要终点
- Microplastics
研究概览
简要总结
Plastic particles known as microplastics are now a ubiquitous part of the environment. Human exposure to microplastics occurs through the consumption of contaminated food and polluted air, which affect the intestinal system. Several studies have detected the presence of microplastics in various parts of the human digestive system, e.g., in feces. Unfortunately, little is known about the presence of microplastics in the mouth as the primary part of the digestive system. Periodontal pockets can be considered an ideal deposition site for microplastics. Since microplastics are suspected of being an immunomodulatory factor, there is great interest in their presence in subgingival plaque and their possible exacerbation of chronic inflammatory diseases such as periodontitis. The following study aims to clarify the presence, classification, and concentration of microplastics in subgingival plaque. No comparable study has been identified to date.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 18 and over
- •Gender: Female / male / diverse
- •who have been diagnosed with stage III and IV periodontitis.
- •who have not yet started periodontal treatment.
- •who still have at least 20 teeth. Providing written consent to participate in the study.
排除标准
- •who have already been treated for periodontitis
- •who have already undergone/begun periodontitis treatment
结局指标
主要结局
Microplastics
时间窗: one year
number of patients with periodontitis with microplastics in periodontal pockets, quantification of microplastic particles in periodontal pockets, qualitative analysis of microplastic
次要结局
未报告次要终点
研究者
Hady Haririan
Prof.
Sigmund Freud PrivatUniversitat
