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临床试验/NCT07231198
NCT07231198尚未招募不适用

Detection of Microplastics in Patients With Periodontitis - a Cross-sectional Study

Sigmund Freud PrivatUniversitat0 个研究点目标入组 25 人开始时间: 2026年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
25
主要终点
Microplastics

研究概览

简要总结

Plastic particles known as microplastics are now a ubiquitous part of the environment. Human exposure to microplastics occurs through the consumption of contaminated food and polluted air, which affect the intestinal system. Several studies have detected the presence of microplastics in various parts of the human digestive system, e.g., in feces. Unfortunately, little is known about the presence of microplastics in the mouth as the primary part of the digestive system. Periodontal pockets can be considered an ideal deposition site for microplastics. Since microplastics are suspected of being an immunomodulatory factor, there is great interest in their presence in subgingival plaque and their possible exacerbation of chronic inflammatory diseases such as periodontitis. The following study aims to clarify the presence, classification, and concentration of microplastics in subgingival plaque. No comparable study has been identified to date.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged 18 and over
  • Gender: Female / male / diverse
  • who have been diagnosed with stage III and IV periodontitis.
  • who have not yet started periodontal treatment.
  • who still have at least 20 teeth. Providing written consent to participate in the study.

排除标准

  • who have already been treated for periodontitis
  • who have already undergone/begun periodontitis treatment

结局指标

主要结局

Microplastics

时间窗: one year

number of patients with periodontitis with microplastics in periodontal pockets, quantification of microplastic particles in periodontal pockets, qualitative analysis of microplastic

次要结局

未报告次要终点

研究者

发起方
Sigmund Freud PrivatUniversitat
申办方类型
Other
责任方
Principal Investigator
主要研究者

Hady Haririan

Prof.

Sigmund Freud PrivatUniversitat

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