Ultrasonography Guided Brain Lesions Resection: a Tool for a Real Time Intraoperative Neuronavigation
试验速览
- 阶段
- 不适用
- 入组人数
- 1
- 主要终点
- Extent of resection of the lesion
研究概览
简要总结
- Evaluate the clinical value of intraoperative ultrasonography as a real-time guidance
- Combination of data of MRI Tractography and intra operative ultrasonography will be useful in good localization of lesions or not .
- Maximal safe resection .
详细描述
Accurate pre and intraoperative localization of Brain lesions is a challenge in neurosurgery specially deep intra cerebral lesions. Stereotaxy and neuronavigator played a major role in preoperative and intraoperative evaluation of exact location of intra cerebral lesions, the main drawbacks of using steriotaxy and neuronavigator that they are time consuming, complicated and expensive.(1) Nowadays we use MRI Tractography as preoperative imaging to localize lesions and there relation to neural tracts specially in eloquent brain areas, and also intraoperative ultrasonography Which act as a real-time, unexpansive and relatively simple tool for intraoperative visualization of the lesion's location, size, extent and its relationship with the surrounding tissue, also it can reveal the lesion's blood supply, it can measure the rate and direction of arterial blood flow.(2,3,4) Intraoperative ultrasonic imaging was first applied as a real-time navigation system in neurosurgery in 1980. (5) In this research we will combine the use of preoperative MRI tractography with intra operative ultrasonography in accurate localization of brain lesions and its relation with important tracts and if this combination will be beneficial and add to the safety of excision of lesions or not.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Month 至 70 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are diagnosed to have Intracranial lesions Patients with recurrent lesions
排除标准
- •Patients who are unfit for surgery Patients who have multifocal lesions
结局指标
主要结局
Extent of resection of the lesion
时间窗: 48 hours
Extent of resection of the lesion evaluated by comparing pre operative and post operative MRI
次要结局
- post operative complication(one month)
研究者
Sarah Ahmed Saad
resident doctor, neurosurgery department
Assiut University
