Study on the Links Between Perception and Action in Schizophrenia, "Upside Down, Give me the Handle"
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- response time
研究概览
简要总结
In schizophrenia, dislocation of psychic functions involving a loss of contact with reality is frequently found. A fragmentation of motor and sensory perceptions could be held responsible (Fuchs, 2005). However, automatic integration between perception and action is the necessary condition to be in "relationship with the world." Affordance is the experimental link between object perception and actions potentially associated (Gibson (1977, 1979) explored by Stimulus Response Compatibility (SRC) paradigm. The existence of visual motor neurons leads us to postulate that the affordance effect can be assisted by a visuomotor priming of a hand in a position to grasp. With Tucker & Ellis sensory motor compatibility task, we study the capacity of affordance in schizophrenia, as well as the impact of perceptual motor priming on these affordance effects.
详细描述
All participants will perform cognitive tasks: reaction time (Alert TEA, Zimmermann and Fimm, 2005), Edinburgh laterality questionnaire (Oldfield, 1971), IQ test (IQ: PM38, Raven, 1960), and the PANSS (Positive and Negative Syndrome Scale, Kay et al., 1987). Controls will only have the first three tasks (cognitive spots Alert and laterality). Then all will perform all tasks in successive order (task 1 and task 2). For both tasks, photographs of 20 objects of everyday life typical grip with one hand are presented in 4 orientations. The instruction is to say if the object is presented upright or inverted; The second task differs from the first only by the introduction of a prime: presenting a hand in position "catching" before the picture of an object
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For patients:
- •a DSM-IV diagnosis of schizophrenia (men or women),
- •no change in antipsychotic medication and clinical status within four weeks prior to the study
排除标准
- •For patients and control group Inclusion criteria
- •Age ≥ 18 years et ≤ 50 years
- •Exclusion Criteria:
- •History of head trauma,
- •neurological disease with cerebral repercussion or not stabilized serious physical illness;
- •psychotropic medication,
- •disorders related to the use of a psychoactive substance (abuse, dependence or withdrawal);
结局指标
主要结局
response time
时间窗: day 1
The gain provided by the compatible vs incompatible conditions (ms response time)
次要结局
未报告次要终点