ACTRN12609000943246招募中不适用
Effects of acute and longer-term energy restriction in lean and obese subjects on antropyloroduodenal motility, gut hormones, appetite and energy intake in response to duodenal nutrients and on oral fat perception
A/Prof Christine Feinle-Bisset0 个研究点目标入组 30 人开始时间: 2009年11月3日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Prevention
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 55 Years(—)
- 性别
- Male
入选标准
- •Subjects will all be males between age 18 -55 years, with a body mass index (BMI) of 18 - 25 kg/m2 for lean and between 30 -35 kg/m2 for obese. Lean subjects will be required to be unrestrained eaters, consume less than 20g of alcohol per week, be non-smokers, free of gastrointestinal or chronic disease and not currently taking medication.
排除标准
- •Each subject will be questioned prior to the study to exclude:
- •(1)significant gastrointestinal symptoms; disease or surgery
- •(2)current use of medications which may alter gastrointestinal motor function or appetite
- •(3)diabetes mellitus (fasting glucose >6.9 mmol/l and/or glycated haemoglobin =6.2 %)
- •(4)epilepsy
- •(5)cardiovascular or respiratory disease
- •(6)any other significant illness as assessed by the investigator
- •(7)allergy to local anaesthetic
- •(8)intake of > 20 g alcohol on a daily basis
- •(9)smokers
- •(10)individuals with food intolerances, allergies or vegetarians
研究者
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