A Single-center Observational Study to Examine the Occurrence of Ventricular Arrhythmias After Pulmonary Vein Isolation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 111
- 试验地点
- 1
- 主要终点
- Ventricular arrhythmias
研究概览
简要总结
The investigators study aimed to observe the occurrence of new premature ventricular complexes and other ventricular arrhythmias after pulmonary vein isolation.
详细描述
Atrial fibrillation is the most common arrhythmia with a lifetime risk for development of over 20%. Pulmonary vein isolation is now established as therapy of choice for patients with symptomatic atrial fibrillation. It is well known that this interventional therapy inevitably modulates the intracardiac autonomic nervous system. While this ablation might alter atrial electrophysiology beneficially, the impact on ventricular electrophysiology remains unclear.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years
- •Paroxysmal atrial fibrillation scheduled to undergo pulmonary vein isolation
排除标准
- •Age < 18 years
- •Persistent atrial fibrillation
- •Life expectancy less than 12 months
- •Acute myocardial infarction, coronary artery bypass graft surgery, open heart surgery, or percutaneous transluminal coronary angioplasty within less than 3 months prior to inclusion
- •Documentation of >30 premature ventricular complexes per hour, salvos or ventricular tachycardias prior to atrial fibrillation ablation
结局指标
主要结局
Ventricular arrhythmias
时间窗: one year
Number of patients with premature ventricular complexes, ventricular tachycardias or ventricular fibrillation.
次要结局
- Arrhythmia recurrence(one year)
研究者
Prof. Dr. Christian Meyer
Prof. Dr.
Universitätsklinikum Hamburg-Eppendorf