跳至主要内容
临床试验/NCT02399891
NCT02399891Unknown不适用

Acute Myocardial Infarction Quality Assurance Project

Dr. Derek Exner1 个研究点 分布在 1 个国家目标入组 6,000 人开始时间: 2011年12月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
6,000
试验地点
1
主要终点
Mortality

研究概览

简要总结

Cohort study aimed at evaluating the incidence of left ventricular (LV) dysfunction after myocardial infraction (MI) and assessing the prognostic utility of change in ejection fraction (EF) over the initial 12 months after MI.

详细描述

Background

Patients suffering a myocardial infraction (MI) may have from minimal to extensive myocardial damage. While severe left ventricular (LV) dysfunction that persists beyond the initial 2-3 months of an MI is a predictor of sudden death, the prognostic significance of less severe LV dysfunction after MI is unclear.

There is significant clinical value in quantifying LV function after the recovery phase of an MI. This information is vital in guiding the breadth and duration of therapies known to improve prognosis (beta-blockers, ACE inhibitors, angiotensin blockers, anticoagulants, and others). Further, it will identify patients in whom other therapies, such as an implantable cardioverter defibrillator (ICD), are recommended. Yet, no guidelines to guide clinical decision making in terms of collecting follow-up ejection fraction (EF) data in such patients who do not also have overt heart failure.

Purpose The Acute Myocardial Infarction Quality Assurance (AMIQA) project proposes to

  1. document clinical practice by collecting data on the proportion of patients with initial LV dysfunction after MI without a follow-up EF assessment arranged,
  2. collect follow-up EF data in patients with initial LV dysfunction post-MI and evaluate the prognostic significant of EF early and late after MI as well as factors associated with the change in value, and
  3. educate physicians regarding the importance of EF reassessment after MI.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • confirmed MI

排除标准

  • 未提供

结局指标

主要结局

Mortality

时间窗: 2 years

次要结局

  • Ejection Fraction(12 months)
  • Heart Failure Hospitalization(2 years)

研究者

发起方
Dr. Derek Exner
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Dr. Derek Exner

Professor

University of Calgary

研究点 (1)

Loading locations...

相似试验