Case-control Study of Risk Factors for Recurrence of Primary Bile Duct Stones
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 2
- 试验地点
- 1
- 主要终点
- The association between existence of periampullary diverticulum and recurrent CBD stone
研究概览
简要总结
Recurrent common bile duct stone is one of the risk factors of recurrent cholangitis. However, the exact pathophysiology or mechanism of recurrent cholangitis has not been established. Periampullary diverticulum and narrow angle of common bile duct have been postulated as risk factors of recurrent common bile duct stone. The aim of this study was to evaluate the association between periampullary dierticulum, angle of common bile duct and recurrent common bile duct stone.
详细描述
Recurrent common bile duct stone is one of the risk factors of recurrent cholangitis. However, the exact pathophysiology or mechanism of recurrent cholangitis has not been established. Periampullary diverticulum and narrow angle of common bile duct have been postulated as risk factors of recurrent common bile duct stone. The aim of this study was to evaluate the association between periampullary dierticulum, angle of common bile duct and recurrent common bile duct stone.
This study is patient-control setting study. Firstly, from July 2007 through February 2014, all the patients who were performed ERCP will be enrolled. The inclusion criteria is the patients with common bile duct stone. The exclusion criteria is patients with biliary stenosis, PSC, retained GB stone, or who were lost to follow-up. The main outcome is the association between periampullary diverticulum, common bile duct angle, and recurrent CBD stone. This will be evaluated by univariate and multivariate analyses.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who were performed ERCP due to CBD stone or calculous cholangitis
排除标准
- •Patients with biliary stricture, PSC, retained GB stone, or who were lost to follow-up.
结局指标
主要结局
The association between existence of periampullary diverticulum and recurrent CBD stone
时间窗: retrospective (up to 8 years)
The association between existence of periampullary diverticulum and recurrent CBD stone will be assessed by univariate analysis.(unit of analysis: odds ratio, statistical method: Fisher's exact test)
次要结局
- The association between common bile duct angle and existence of recurrent CBD stone(retrospective (up to 8 years))
研究者
Jai Hoon Yoon
Professor Jai Hoon Yoon
Chuncheon Sacred Heart Hospital