跳至主要内容
临床试验/NCT06142630
NCT06142630已完成不适用

The Effects of Different Positions on the Diffusion and Blockade Effect of Ultrasound-guided Erector Spinae Plane Block

Nanjing First Hospital, Nanjing Medical University1 个研究点 分布在 1 个国家目标入组 84 人开始时间: 2023年11月21日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
84
试验地点
1
主要终点
Incidence and number of local anesthetic diffusion segment into the paravertebral space

研究概览

简要总结

After the completion of erector spinae plane block, the patient maintains different positions to assess the diffusion of local anesthetic and the effect of the block.

详细描述

Eighty-four patients were selected to undergo CT guided puncture localization of pulmonary nodules under local anesthesia, and the patients were divided into groups using a computer-generated random number in a ratio of 1:1:1. To ensure objectivity, a nurse who was not involved in the study prepared a sealed opaque envelope containing grouping information. Randomly divide patients into three groups: supine position group (S group, 28 patients), prone position group (P group, 28 patients), and lateral position group (L group, 28 patients). The patients underwent ultrasound guided ESPB on the puncture side before CT puncture localization. Ultrasound guided ESPB method: Using an ultrasound high-frequency linear array probe (5-13MHz, Sonosite, USA), the probe is placed parallel to the spine on the surface of the transverse process tip of the seventh thoracic vertebrae. Under ultrasound, the transverse process and spinal muscles are clearly exposed. Then, a short inclined plane puncture needle is used, and the needle is inserted from the head side using in-plane technology. After the needle tip reaches between the transverse process and erector spinae muscles, 1ml of physiological saline is injected using water separation technology to confirm the position of the needle tip, Then inject 30ml of local anesthetic solution (0.75% ropivacaine 15ml+iohexol 15ml). After the block was completed, patients in Group S remained in a supine position; Patients in group L maintained the blocking side above; Patients in Group P maintained a prone position. After 30 minutes of block completion, CT scan and puncture localization were performed, following with 3D reconstruction. The primary outcome was LA-contrast spread to the paravertebral space.The second outcomes were as follow: 1. spread to the neural foramina 2. cranio-caudal spread 3. spread to the epidural space 4. spread to the intercostal space.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Double (Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients received CT guided puncture localization of pulmonary nodules under local anesthesia

排除标准

  • Allergic to local anesthetic
  • History of opioid abuse
  • Severe skin infection
  • Peripheral neuropathy
  • Dysfunction of blood coagulation

结局指标

主要结局

Incidence and number of local anesthetic diffusion segment into the paravertebral space

时间窗: 30 minute after completion of the ESPB block

Observation of local anesthetic spread spread into the paravertebral space with CT by a researcher who was blinded to group allocation

次要结局

  • Sensory loss of cold(30 minute immediately after completion of the nerve block)
  • Diffusion of local anesthetic into intercostal space(30 minute after completion of the block)
  • Diffusion of local anesthetic into the epidural space(30 minute after completion of the block)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验

Different Positions on the Diffusion and Blockade... | 临床试验