NCT00830986已完成不适用
Cognition Following Computer Assisted Total Knee Arthroplasty: A Prospective Cohort Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 主要终点
- Folstein Mini Mental State Examination (MMSE)
研究概览
简要总结
A significant number of patients experience postoperative cognitive changes following total joint arthroplasty. Among other causes, the mental status change may be the result of fat and bone marrow debris embolization. We hypothesized that the use of computer assisted total knee arthroplasty, which does not utilize intramedullary alignment rods, would produce less fat and bone marrow debris embolization and, hence, fewer mental status changes.
详细描述
Inclusion criteria
- Primary, cemented knee arthroplasty
- Unilateral or bilateral TKA
Exclusion criteria
- Patient is unable to speak English
- Unable to read and write
- Patient with history of psychiatric disorders (Depression, Schizophrenia, anxiety, bipolar dis.)
- Patients with history of IV drug abuse
- Previous history of dementia
- Patients on mental status changing medications
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Primary, cemented knee arthroplasty
- •Unilateral or bilateral TKA
排除标准
- •Patient is unable to speak English
- •Unable to read and write
- •Patient with history of psychiatric disorders (Depression, Schizophrenia, anxiety, bipolar dis.)
- •Patients with history of IV drug abuse
- •Previous history of dementia
- •Patients on mental status changing medications
结局指标
主要结局
Folstein Mini Mental State Examination (MMSE)
时间窗: 6 Months Post-Operative
次要结局
未报告次要终点
研究者
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