The Dose of Sugammadex for Rapid Reversal of Profound Neuromuscular Block in Young and Elderly Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- The dose of sugammadex for recovery of the TOF ratio to 0.9 within 2 minutes from profound neuromuscular block
研究概览
简要总结
To find out the dose of sugammadex for recovery of the TOF ratio to 0.9 within 2 minutes from profound rocuronium-induced neuromuscular block in young and elderly adult patients.
详细描述
A previous study reported that elderly patients required a longer time to recover from rocuronium induced neuromuscular block compared to younger patients. Therefore, the aim of this study is to find out the dose of sugammadex for rapid recovery from profound neuromuscular block in young and elderly adult patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •20-40 years or ≥70 years ASA class I-II patients who received surgery less than 2 hours.
排除标准
- •anticipated difficult intubation
- •neuromuscular, hepatic or renal disorders
- •drug allergy
- •body mass index >30 kg/m2 or body mass index <18 kg/m2
- •emergency surgery
研究组 & 干预措施
Young adults
To find out the the dose of sugammadex for recovery of the TOF ratio to 0.9 within 2 minutes from profound neuromuscular block : Dixon's up-and-down method
干预措施: Sugammadex (Drug)
Elderly adults
To find out the the dose of sugammadex for recovery of the TOF ratio to 0.9 within 2 minutes from profound neuromuscular block : Dixon's up-and-down method
干预措施: Sugammadex (Drug)
结局指标
主要结局
The dose of sugammadex for recovery of the TOF ratio to 0.9 within 2 minutes from profound neuromuscular block
时间窗: 2 hour
次要结局
未报告次要终点
研究者
So Yeon Kim
Assistant professor
Severance Hospital