KCT0000012招募中未知
Effect of palonosetron on patient-controlled analgesia related nausea and vomiting after thyroidectomy (comparison with ondansetron and ramosetron)
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 20(Year) 至 65(Year)（—）
- 性别
- Female
入选标准
- •Patients undergoing thyroid surgery, with a risk of PONV exceeding 60% are selected according to the expected risk for PONV using the simplified risk score of Apfel et al. The 4 risk factors considered in this score are female gender, nonsmoking, the use of postoperative opioids, and prior history of motion sickness or PONV; the presence of 0, 1, 2, 3, or 4 of these risk factors correspond to approximately 10, 20, 40, 60, and 80% risk for PONV, respectively. Basic inclusion criteria are nonsmoking, female patients, and use of postoperative opioid.
排除标准
- •Patients who have severe impairment of bowel motility, insulin-dependent diabetes mellitus, pregnancy or breastfeeding, administration of antiemetic medication within 24 hours before surgery, systemic treatment with steroids within 24 hours before surgery or during 48 hours after surgery, obesity (body mass index >=35 kg/m2),impaired renal and/or hepatic function, or require radical neck dissection
研究者
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1 期
Can the drug palonosetron reduce the risk for postdischarge nausea and vomiting the days after ambulatory surgery?ausea and vomiting in the home (after discharge) after day-case surgery under general anesthesia-MedDRA version: 18.1Level: HLTClassification code 10028817Term: Nausea and vomiting symptomsSystem Organ Class: 100000004856MedDRA version: 18.1Level: LLTClassification code 10036285Term: Postoperative nauseaSystem Organ Class: 100000004863MedDRA version: 18.1Level: LLTClassification code 10036901Term: Prophylaxis against postoperative nausea and vomitingSystem Organ Class: 100000004865MedDRA version: 18.1Level: LLTClassification code 10054182Term: Perioperative nausea and vomiting prophylaxisSystem Organ Class: 100000004865MedDRA version: 18.1Level: LLTClassification code 10028818Term: Nausea postoperativeSystem Organ Class: 100000004863EUCTR2015-003956-32-SEmeå University700
Unknown
不适用
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尚未招募
不适用
Two groups of Drugs are compared to find out their efficacy in preventing Post operative Nausea and Vomiting.CTRI/2021/11/037949Sree balaji medical college and hospital
已完成
不适用
The effect of combination of palonosetron and aprepitant for the prevention of postoperative nausea and vomiting in women patients using intravenous patient-controlled analgesia: combination of palonosetron and aprepitant vs palonosetron alone.KCT0002433Soon Chun Hyang University Hospital Seoul100