Effects of common topical glaucoma therapy on optic nerve head blood flow autoregulation during increased arterial blood pressure and artificially elevated intraocular pressure in healthy humans

Department of Clinical Pharmacology, Medical University of Vienna0 个研究点目标入组 54 人开始时间: 2006年1月5日最近更新: 2013年6月10日

适应症

试验速览

暂无简介。

•54 healthy male subjects
•Men aged between 19 and 35 years, nonsmokers
•-Body mass index between 15th and 85th percentile (Must et al. 1991)
•-Normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant
•-Normal ophthalmic findings, ametropy < 1 Dpt.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years)
•F.1.3.1 Number of subjects for this age range

•-Regular use of medication, abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preceding the study
•-Treatment in the previous 3 weeks with any drug
•-Symptoms of a clinically relevant illness in the 3 weeks before the first study day
•- Blood donation during the previous 3 weeks
•- Presence of intraocular pathology: ocular hypertension, glaucoma, retinal vasculopathy or other retinal diseases

发起方

Department of Clinical Pharmacology, Medical University of Vienna