Customization of Cardiac Readaptation Based on Force-velocity Profile and Heart Rate Variability: A Controlled and Randomized Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- The root mean square of successive differences in heart rate or RMSSD
研究概览
简要总结
Cardiac readaptation aims to mitigate cardiovascular risks and enhance the quality of life among coronary patients. Our research laboratory has an international expertise in training optimization in top-athletes and a previous study has demonstrated the efficacy of optimizing cardiac rehabilitation through the power-force-velocity profile (PFVP). The findings exhibited significant improvements in aerobic capacity, muscular strength, and cardiovascular parameters among patients who were trained based on their PFVP. Guided training utilizing heart rate variability (HRV) is also garnering increasing interest as a means to optimize training load and promote recovery
详细描述
Our study aims to evaluate the application of HRV in regulating training load based on fatigue levels in cardiac rehabilitation patients utilizing the PFVP framework.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute Coronary Syndrome treated in the last 6 months
- •Medical revascularization (angioplasty ± stenting) or surgical (coronary artery bypass)
- •Initial CPETt: MPA ≥ 60w in women and ≥80w in men
- •Informed consent
排除标准
- •Significant co-morbidities limited practice of physical activity
结局指标
主要结局
The root mean square of successive differences in heart rate or RMSSD
时间窗: Baseline to 2 months
The root mean square of successive differences in heart rate or RMSSD will be measured from a nocturnal Holter ECG recording at the end of 8 weeks of exercise retraining and compared with the initial pre-training value. weeks of exercise re-training and compared with the initial pre-training value.
次要结局
- Value of maximum oxygen consumption(Baseline to 2 months)
- Assessment of the ANS sympathetic branch(Baseline to 2 months)
- Assessment of the ANS parasympathetic branch(Baseline to 2 months)
- non-invasive measurement of arterial stiffness(Baseline to 2 months)
- assessment of PFVP evolution(Baseline to 2 months)
- assessment of physical a activity and sedentary behavior(Baseline to 2 months)
- quality of life assessment(Baseline to 2 months)
- measurement of upper and lower limb muscle strength(Baseline to 2 months)
- assessment of subjective fatigue(Baseline to 2 months)
- biological data(Baseline to 2 months)