The Evaluation of White Matter Intensities in Patients with Pediatric Epilepsy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 173
- 试验地点
- 1
- 主要终点
- The Evaluation of White Matter Intensities in Patients with Pediatric Epilepsy
研究概览
简要总结
Aim: Neuroimaging is an important tool, in combination with a detailed medical history, physical examination, and electroencephalography, in the diagnosis and classification of epilepsy. White matter hyperintensities (WMHs) are bright areas of high signal intensity seen in white matter at T2-weighted MRI. Researchers aimed to evaluate whether white matter hyperintensities are more common in children with epilepsy.
Material-method: Patients who underwent cranial MRI with diagnoses of epilepsy based on International League Against Epilepsy (ILAE) criteria at the Balıkesir University Medical Faculty Pediatric neurology clinic, Türkiye, between 01.08.2019 and 01.03.2024 and patients who underwent cranial MRI during the same period due to indications other than epilepsy, such as headache, syncope, and vertigo, were included in the study. Written informed consent was received from all patients.
详细描述
Aim: Neuroimaging is an important tool, in combination with a detailed medical history, physical examination, and electroencephalography, in the diagnosis and classification of epilepsy. White matter hyperintensities (WMHs) are bright areas of high signal intensity seen in white matter at T2-weighted MRI. Researchers aimed to evaluate whether white matter hyperintensities are more common in children with epilepsy.
Material-method: Patients who underwent cranial MRI with diagnoses of epilepsy based on International League Against Epilepsy (ILAE) criteria at the Balıkesir University Medical Faculty Pediatric neurology clinic, Türkiye, between 01.08.2019 and 01.03.2024 and patients who underwent cranial MRI during the same period due to indications other than epilepsy, such as headache, syncope, and vertigo, were included in the study. Written informed consent was received from all patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 5 Years 至 16 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Cranial MRI during the same period due to indications other than epilepsy;
- •syncope and
排除标准
- •Patients with neuropsychiatric disorders;
- •depression,
- •psychotic disorders,
- •autism spectrum disorder History of medication use for any chronic disease other than seizure medication, History of vascular disease ;
- •Collagen tissue diseases;
- •juvenile rheumatoid arthritis,
- •polyarteritis nodosa,
- •Kawasaki disease Demyelinating disease
- •acute demyelinating disease (ADEM),
- •Multiple sclerosis Acute symptomatic seizure or a single unprovoked seizure, İncomplete file data, or MRI performed at a location other than our hospital
结局指标
主要结局
The Evaluation of White Matter Intensities in Patients with Pediatric Epilepsy
时间窗: 01.08.2019 and 01.03.2024
Better understanding the association between pediatric epilepsy patients and white matter changes.
次要结局
未报告次要终点
研究者
Aysen Orman
Associate Prof
Mersin University