Effectiveness and Neuropsychological Predictors of Guided Self-Help for OCD
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 试验地点
- 2
- 主要终点
- Change in Yale-Brown Obsessive-Compulsive Scale (Y-BOCS)
研究概览
简要总结
The primary aim of this study is to learn about who is most likely to benefit from guided self-help (GSH) for obsessive-compulsive disorder (OCD).
详细描述
40 Participants with OCD will be recruited. They will be given access to OC Fighter, an internet OCD treatment program. During the 17 week program, participants will meet with a therapist 9 times. Assessments will occur at pretreatment, post-treatment, 3-month follow up and 6-month follow up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 69 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Principal or co-principal diagnosis of OCD
- •Clinical global impression score greater than or equal to 4
- •Y-BOCS score great than or equal to 8
- •Fluency in English
- •Capacity to understand the nature of the study and willingness to sign informed consent form
排除标准
- •Active manic episode, psychosis, pervasive developmental disorder, mental retardation
- •Concurrent OCD psychotherapy
- •Current threat of harm to self or others
- •Previous adequate trial of therapist-administered or self-administered exposure and response prevention for OCD
结局指标
主要结局
Change in Yale-Brown Obsessive-Compulsive Scale (Y-BOCS)
时间窗: Baseline (pretreatment), 17-weeks (posttreatment), and 6 month-follow-up
The Y-BOCS is a semi-structured interview that assesses severity of obsessions and compulsions. The total score is reported here and ranges from 0 to 40 with higher scores indicating more severe OCD symptoms.
Responder Status
时间窗: Week 17 (post-treatment) and 6-month follow-up
Participants who experienced a clinically significant change in Y-BOCS score defined as posttreatment YBOCS score that (a) has decreased by a reliable level (at least 1.96 times the standard deviation of that measure, taking into account the reliability of the measure itself; in this case, a decrease of 5 points or more), and (b) is within the nonclinical range of scores (in this case, a score of 13 or below).
次要结局
未报告次要终点