Heart Failure Burden and Heart Failure Risk in the General Population in Norway: "The HUNT for Heart Failure" Risk Score
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36,511
- 试验地点
- 1
- 主要终点
- Time to incident heart failure event
研究概览
简要总结
In this population study aim is to evaluate risk factors for heart failure and combine these into a new heart failure risk score.
Secondly, the heart failure risk score will be internally and externally validated, and compared with established heart failure risk scores. Additionally, the prevalence of heart failure as well as the distribution of the heart failure risk score in the general population will be evaluated.
详细描述
Explore which clinical risk factors or patient characteristics in a general population that are associated with increased risk for heart failure events and combine these into a new population-based heart failure risk score ("The HUNT for heart failure risk score") for predicting heart failure risk
Validate the newly developed heart failure risk score internally in the HUNT2 database
Compare the predictive ability of the new heart failure risk score with established heart failure risk scores (the ABC Health HF risk score, the Framingham HF risk score) and an established Norwegian cardiovascular risk score (NORRISK 2)
Estimate the prevalence of likely ("undiagnosed") heart failure , i.e., patients at high risk of HF, in a general population by using both the established heart failure risk scores and the newly developed heart failure risk score, and compare the heart failure event rate between those at high risk of heart failure and those with established heart failure.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participation in the third or second wave of the HUNT study
排除标准
- •Not willing to participate
- •Missing vital data
结局指标
主要结局
Time to incident heart failure event
时间窗: 10 years
Time to first heart failure hospitalization or heart failure related visit at the out-patient clinic (events defined according to the ESC 2016 heart failure guidelines)
次要结局
- Time to death from any cause(10 years)
- Time to first heart failure event or death from any cause(10 years)
- Validity of heart failure risk score(10 years)
