CTRI/2009/091/000590招募中1 期
Stem cell therapy- Cellular Cardio myoplasty for patients with severe ventricular dysfunction
Frontier Lifeline PvtLtd0 个研究点目标入组 90 人开始时间: 待定最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 90
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Patients aged between 0 to 60 years presenting with Dilated Cardiomyopathy or coronary artery disease (CAD) are enrolled. Patients with ventricular ejection fraction (LVEF) less than 35% are eligible for enrollement.
排除标准
- •1. Sustained ventricular tachycardia in a 24 hour ECG.
- •2. Chronic atrial fibrillation.
- •3. Less than 6 months since last episode of cerebral
- •infarction.
- •4. Less than 6 months since last coronary angioplasty or
- •less than 3 months since last bypass surgery.
- •5. Patients with unstable angina, with a treatment rating
- •of 3 in the Braunwald system, but a severity of III and a
- •clinical rating of B or C.
- •6. Presence of left ventricular thrombus by
- •echocardiography.
- •7. Patient with a malignant tumour.
- •8. Patient with diabetic proliferating retinopathy** (new
- •Fukuda classification BI to BV).
- •9. Patients with chronic rheumatoid arthritis.
- •10. Patient with haematological disease (leukaemia,
- •myeloproliferative disease or myelodysplastic
- •11. Patients for whom cranial MRA reveals cerebral
- •12. Patients for whom abdominal CT or ultrasonography
- •reveals splenomegaly.
- •13 Patients with cirrhosis of the liver.
- •14. Patients who cannot discontinue warfarin.
- •15. AST (GOT) exceeding 100 IU/L or ALT (GPT)
- •exceeding 100 IU/L.
- •16. Patients for whom it is impossible to perform both
- •cardiac MRI and left ventriculography (LVG).
- •17. Any other reason that the Clinical supervisors or
- •clinical Researchers may have for considering a case
- •unsuitable for the study.
研究者
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