Utility of A Clinical Repertory To The Dictionary Of Materia Medica By Dr. J H Clarke in the management of cases of Gastroesophageal Reflux Disease.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- To evaluate the effect of individualized homoeopathic medicines selected using A Clinical Repertory To The Dictionary of Materia Medica by Dr. J. H. Clarke in the management of gastroesophageal reflux disease using a validated GERD symptom score (GERD-Q scale) before and after treatment.
Study Overview
Brief Summary
Gastroesophageal reflux disease (GERD) is a common chronic gastrointestinal disorder that significantly affects the quality of life of affected individuals. Despite the availability of conventional treatment, many patients continue to experience persistent symptoms, emphasizing the need for individualized therapeutic approaches. Homoeopathy emphasizes individualized treatment based on the totality of symptoms, and repertorization forms the foundation of remedy selection.
This prospective, open-label, single-arm clinical study is designed to evaluate the utility of A Clinical Repertory to the Dictionary of Materia Medica by Dr. J. H. Clarke as a repertorial tool in the management of cases of gastroesophageal reflux disease. Patients fulfilling the eligibility criteria will be enrolled from the outpatient department of the institution. Detailed homoeopathic case taking will be carried out for each patient, followed by repertorial analysis using A Clinical Repertory to the Dictionary of Materia Medica by Dr. J. H. Clarke for the prescription of individualized homoeopathic medicines.
The outcome of the study will be assessed using a validated GERD symptom score, namely the GERD-Q scale, at baseline and during follow-up over a period of six months. The study also aims to observe the clinical presentation of gastroesophageal reflux disease in the study population. The results of this study may help establish the clinical utility of A Clinical Repertory to the Dictionary of Materia Medica by Dr. J. H. Clarke in the individualized homoeopathic management of GERD.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients willing to provide written informed consent for the study.
- •Diagnosed cases of GERD presenting with evidence of endoscopic findings.
- •Patients with uncomplicated GERD presenting with symptoms of heartburn and regurgitation, and a GERD-Q score more than or equal to 8 confirming clinical diagnosis.
- •Endoscopy will be advised only in patients showing alarming symptoms (such as dysphagia, odynophagia, unintentional weight loss, gastrointestinal bleeding, anaemia or persistent vomiting) or if clinically indicated.
Exclusion Criteria
- •Patients with advanced pathology of GERD or malignancy.
- •Cases suffering from uncontrolled systemic illness or life-threatening conditions.
- •Patients already taking acid suppressing medications or other treatment and not willing to leave it.
- •Pregnant and lactating women.
- •Patients who are immunocompromised.
- •Patients who are unwilling to take part and not giving consent for the study.
Outcomes
Primary Outcomes
To evaluate the effect of individualized homoeopathic medicines selected using A Clinical Repertory To The Dictionary of Materia Medica by Dr. J. H. Clarke in the management of gastroesophageal reflux disease using a validated GERD symptom score (GERD-Q scale) before and after treatment.
Time Frame: Baseline to 6 months
Secondary Outcomes
- To study the clinical presentation of gastroesophageal reflux disease in patients reporting to the OPD and to assess the improvement in individual GERD symptoms following individualized homoeopathic treatment.(30 days)
Investigators
Dr Akansha Parihar
State National Homoeopathic Medical College And Hospital