Effect of Sonic Activation of Irrigant on Post Operative Pain After Root Canal Treatment

Not Applicable

• Conditions: Post Operative Pain; Root Canal Therapy

• Registration Number: NCT07062419
• Lead Sponsor: CMH Lahore Medical College and Institute of Dentistry

Brief Summary

Fifty-eight patients aged 18-60 years, diagnosed with symptomatic or asymptomatic apical periodontitis will be randomly allocated into two groups: Group A (EndoActivator) and Group B (conventional syringe irrigation). preoperative pain will be evaluated in all patients requiring root canal treatment using visual analogue scale before initiating the procedure.

Postoperative pain will be measured using the Visual Analog Scale (VAS) at 24, 36, 48 hours and one week.

Detailed Description

This randomized clinical study will evaluate the effect of two different irrigation techniques on postoperative pain following root canal treatment in patients with apical periodontitis. A total of 58 patients will be randomly assigned to one of two groups: one group will receive irrigation using the EndoActivator system, while the other group undergo conventional syringe irrigation. The objective is to determine whether the irrigation technique influences the level of postoperative discomfort experienced by patients. Pain levels will be assessed at specific time intervals to track the pattern of recovery and provide insight into the clinical effectiveness of each method in terms of patient comfort.

Study Timeline

• Study Start: 2025-01-01
• Status Verified: 2025-06
• Study First Submitted: 2025-06-20
• Study First Submitted QC: 2025-07-10
• Study First Posted: 2025-07-14
• Primary Completion: 2025-07-25
• Last Update Submitted: 2025-08-14
• Last Update Posted: 2025-08-19
• Study Completion: 2025-08-30

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

• irreversible pulpitis
• symptomatic apical periodontitis
• asymptomatic apical periodontitis
• compliant patients
• sufficient ferrule for post operative restoration

Exclusion Criteria

• periapical abcess
• severe periodontal disease with guarded periodontal prognosis
• teeth with guarded post operative restoration prognosis
• non compliant patients

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
post operative pain using endoactivator	before procedure, after 24 hours, 36 hours , 48 hours, 1 week	post operative pain will be marked on visual analogue scale (VAS). the lower the score the less pain will be and vice versa.; maximum score 10 minimum score 0 0 to 10 depicting no pain to worst pain
post operative pain	before procedure, after 24 hours , 36 hours , 48 hours , 1 week	pain will be evaluatedon visual analogue scale (VAS). the lower the score the less pain will be and vice versa.; maximum score 10 minimum score 0 0 to 10 depicting no pain to worst pain

Trial Locations

Locations (1)

28 Military Dental Centre; 🇵🇰 Lahore, Punjab, Pakistan