NL-OMON36017已完成不适用
Periodontitis and Rheumatoid Arthritis; a link by protein citrullination? A cross-over clinical trial - Periodontitis-RA, cross-over clinical trial
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •RA patients
- •1. Fulfilling the American College of Rheumatology classification criteria for RA (1987)
- •2. Age > 18 years
- •3. Fulfilling the classification criteria of periodontal diseases for generalized severe chronic periodontitis according
- •to the 1999 International Workshop for Classification of Periodontal Diseases and Conditions
排除标准
- •1. Infection or inflammation other than periodontitis or RA
- •2 Present malignancy
- •3. Other conditions which influence the immune system:, diabetes, active thyroid disease, myocardial infarction,
- •stroke or recanalisation of the femoral arteries for claudication <6 months prior to the study
- •4. Pregnancy including a 6-months post-partem period as well as breastfeeding
- •5. Malnutrition
- •6. Alcoholism and drug abuse
- •7. Pharmacological interference: use of corticosteroids >10mg/dag, antibiotic use during 3 months prior to the
- •study, allergy to amoxicillin or metronidazole
- •8. Edentulism
研究者
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