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临床试验/NL-OMON36598
NL-OMON36598已完成不适用

Periodontitis and Rheumatoid Arthritis; a link by protein citrullination? Presence of Anti Citrullinated Protein Antibodies (ACPAs) in periodontitis. - ACPAs in periodontitis

niversitair Medisch Centrum Groningen0 个研究点目标入组 20 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
20

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • 1. Fulfilling the classification criteria of periodontal diseases for generalized severe periodontitis according to the 1999 International Workshop for Classification of Periodontal Diseases and Conditions
  • 2. Age > 18 years

排除标准

  • According to the SENIEUR protocol (1984)
  • 1. Infection or inflammation other than periodontitis.
  • 2. Malignancy, past or present
  • 3. Other conditions which influence the immune system: RA, diabetes, active thyroid disease
  • myocardial infarction, stroke or recanalisation of the femoral arteries for claudication <6 months prior to the study
  • 4. Pregnancy including a 6-months post-partem period as well as breastfeeding
  • 5. Malnutrition
  • 6. Alcoholism and drug abuse
  • 7. Use of corticosteroids >10mg/day, antibiotic use during 3 months prior to the study
  • 8. Edentulism

研究者

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