NL-OMON36598
Completed
Not Applicable
Periodontitis and Rheumatoid Arthritis; a link by protein citrullination? Presence of Anti Citrullinated Protein Antibodies (ACPAs) in periodontitis. - ACPAs in periodontitis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- gum disease
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 20
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Fulfilling the classification criteria of periodontal diseases for generalized severe periodontitis according to the 1999 International Workshop for Classification of Periodontal Diseases and Conditions
- •2\. Age \> 18 years
Exclusion Criteria
- •According to the SENIEUR protocol (1984\)
- •1\. Infection or inflammation other than periodontitis.
- •2\. Malignancy, past or present
- •3\. Other conditions which influence the immune system: RA, diabetes, active thyroid disease
- •myocardial infarction, stroke or recanalisation of the femoral arteries for claudication \<6 months prior to the study
- •4\. Pregnancy including a 6\-months post\-partem period as well as breastfeeding
- •5\. Malnutrition
- •6\. Alcoholism and drug abuse
- •7\. Use of corticosteroids \>10mg/day, antibiotic use during 3 months prior to the study
- •8\. Edentulism
Outcomes
Primary Outcomes
Not specified
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