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临床试验/NL-OMON36011
NL-OMON36011已完成不适用

Periodontitis and Rheumatoid Arthritis; a link by protein citrullination? An observational study. - Periodontitis-RA, observational study.

niversitair Medisch Centrum Groningen0 个研究点目标入组 75 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
75

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • Study group: RA patients
  • 1. Fulfilling the American College of Rheumatology classification criteria for RA (1987).
  • 2. Age > 18 years.
  • Control group: individuals without RA, aged >18 years.

排除标准

  • According to the SENIEUR protocol (1984):
  • 1. Infection or inflammation other than periodontitis or RA.
  • 2. Present malignancy.
  • 3. Other conditions which influence the immune system: diabetes, active thyroid disease, myocardial infarction, stroke or recanalisation of the femoral arteries for claudication <6 months prior to the study.
  • 4. Pregnancy including a 6-months post-partem period as well as breastfeeding.
  • 5. Malnutrition.
  • 6. Alcoholism and drug abuse.
  • 7. Pharmacological interference: use of corticosteroids >10mg/dag, antibiotic use during 3 months prior to the study.
  • 8. Edentulism.

研究者

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