NL-OMON36011
Completed
Not Applicable
Periodontitis and Rheumatoid Arthritis; a link by protein citrullination? An observational study. - Periodontitis-RA, observational study.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- gum disease
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 75
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Study group: RA patients
- •1\. Fulfilling the American College of Rheumatology classification criteria for RA (1987\).
- •2\. Age \> 18 years.
- •Control group: individuals without RA, aged \>18 years.
Exclusion Criteria
- •According to the SENIEUR protocol (1984\):
- •1\. Infection or inflammation other than periodontitis or RA.
- •2\. Present malignancy.
- •3\. Other conditions which influence the immune system: diabetes, active thyroid disease, myocardial infarction, stroke or recanalisation of the femoral arteries for claudication \<6 months prior to the study.
- •4\. Pregnancy including a 6\-months post\-partem period as well as breastfeeding.
- •5\. Malnutrition.
- •6\. Alcoholism and drug abuse.
- •7\. Pharmacological interference: use of corticosteroids \>10mg/dag, antibiotic use during 3 months prior to the study.
- •8\. Edentulism.
Outcomes
Primary Outcomes
Not specified
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