Effect of ascorbic acid in prevention of preterm premature rupture of membrane
Phase 3
- Conditions
- Premature rupture of membranes, unspecifiedPPROM.
- Registration Number
- IRCT201012083580N3
- Lead Sponsor
- Vice chancellor for research, Hamedan University of Medical Sciences and Health Services
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
Pregnant women with gestational age 18 weeks who are suspicious of PPROM.
Exclusion criteria:
1- Lack of follow up patients
2- Lack of cooperation of patients in taking the drug and placebo in time
3- History of surgery on uterus
4- History of cesarean section
5- Experience of artificial insemination pregnancy
6- Smoking
7- Short cervix
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method nconjugated estriol. Timepoint: Is measured once. Method of measurement: special laboratory kit.;Frequency of preterm premature rupture of membranes. Timepoint: 10 weeks after taking drug and plecebo. Method of measurement: questionnaire.
- Secondary Outcome Measures
Name Time Method Complications after delivery. Timepoint: be assessed after delivery. Method of measurement: questionnaire.