Diagnostic Accuracy of Ultrasound and Tumors Markers in Diagnosis of Complex Ovarian Cysts in Adolescent, Histopathological Correlation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Diagnosis of Complex Ovarian Cysts
研究概览
简要总结
Cystic ovarian lesions are more common in adolescences due to onset of hormonal activity in prepubertal age. Most cysts are functional but a malignant etiology must nevertheless always be eliminated.
Most ovarian cysts in adolescents are benign in nature, with 60% being simple ovarian cysts.
Cystic neoplasia may be benign, borderline, or malignant. The large majority are benign or borderline, accounting for 80% and 16%, respectively
详细描述
Cystic ovarian lesions are more common in adolescences due to onset of hormonal activity in prepubertal age. Most cysts are functional but a malignant etiology must nevertheless always be eliminated.
Complex benign cysts are about 16% of all ovarian cysts, :(mature cystic teratoma 55-70%, endometrioma, gonadoblastoma, serous cystadenoma, mucinous cystadenoma, cystadenofibroma).
About 1% of ovarian tumors can be malignant and differential diagnosis with benign ones is sometimes difficult. Concerning the management of such tumors in adolescents for which future fertility is a concern.
Malignant ovarian tumors types are :( Sex cord-stromal tumors:( juvenile granulosa cell tumor is most common about 50% and Sertoli-Leydig cell tumor), Germ cell tumors: (dysgerminoma30%, immature teratoma30%, yolk sac tumor, embryonal carcinoma and polyembryoma) and Epithelial tumors:(serous adenocarcinoma, mucinous adenocarcinoma).
Ultrasonography is a gold standard modality in the evaluation of the female pelvis in adolescence today the method of choice for distinguishing between benign and malignant adnexal pathologies. Using pattern of recognition several types of cysts and tumors can be recognized according to their characteristic appearance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 11 Years 至 21 Years(Child, Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female patients diagnosed by complex ovarian cysts
排除标准
- •simple ovarian cyst < 7cm
- •Any suspected ovarian malignancy
研究组 & 干预措施
Cases with Complex Ovarian Cyst
About 48 female patients suffered from Complex Ovarian Cysts. tumor marker and MRI should be done. If no suspicion of cancer by tumor markers and the patient was Symptomatic and the size of the cysts >5 cm: Laparotomy or Laparoscopic cystectomy and histopathological examination were done.
干预措施: Laparotomy or laparoscopic ovarian cystectomy (Procedure)
结局指标
主要结局
Diagnosis of Complex Ovarian Cysts
时间窗: 3 months
Assessment and Diagnosis of female patients with Complex Ovarian Cysts by ultrasound or tumor markers
次要结局
未报告次要终点
研究者
Ahmed Fathy Ibrahim Mohamed
Resident of Obstetrics and Gynecology
Al-Azhar University
