Day care versus Inpatient Management of nausea and vomiting of pregnancy - D.I.M. trial

Completed

• Conditions: ausea and vomiting of pregnancy (NVP)/ hyperemesis gravidarum (HG); Pregnancy and Childbirth; Excessive vomiting in pregnancy

• Registration Number: ISRCTN05023126
• Lead Sponsor: Cork University Maternity Hospital (Ireland)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-11-10
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 124

Inclusion Criteria

All pregnant women under 22 weeks gestation presenting to the emergency department of Cork University Maternity Hospital (CUMH) are candidates for inclusion in the trial. Patients who fulfil the International Classification Disease (ICD-10) definition of hyperemesis gravidarum (mild and severe) will be enrolled in the study.

Women (no age limits) will be admitted to the study if they have two or more of the following criteria:
1. Ongoing viable intrauterine pregnancy/ pregnancies <22 weeks gestation
2. Persistent vomiting (>3 episodes/ 24 hours) not attributable to other causes
3. Severe nausea not attributable to other causes
4. Dehydration diagnosed by the presence of ketonuria
5. Electrolyte imbalance not attributable to other causes

Exclusion Criteria

Women will not be admitted to the study if any of the following criteria are present:
1. Women with a confirmed urinary tract infection (mid stream urine isolation of a single strain of uropathogen >10^5 bacteria/ml)
2. Women with molar pregnancies
3. Women with non-viable pregnancies
4. Women who have already received treatment for NVP outside of this trial
5. Pregnant women who present who will not be booking at CUMH for their pregnancy or are not resident in the South West of Ireland i.e. day care treatment is not an option
6. Women who do not have a good understanding of English

Study & Design

• Study Type: Interventional
• Study Design: Not specified