Magnetic Stimulation of the Brain in Premenstrual Tensio

Not Applicable

Active, not recruiting

• Conditions: Premenstrual Dysphoric Disorder; F03.600

• Registration Number: RBR-2f3pbms
• Lead Sponsor: niversidade Federal de Pernambuco

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-02-10
• Study Completion: 2023-02-28
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Confirmed diagnosis of premenstrual dysphoric disorder; Age 18 years or older; Regular menstrual cycles, lasting between 21-35 days; Availability to attend the service on the days designated for the intervention.
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Exclusion Criteria

Lifelong diagnosis of depression, bipolar disorder or schizophrenia (confirmed by a psychiatrist); Use of psychotropic drugs (controlled drugs), in the last 04 weeks; Risk of committing suicide; Pregnancy; Absolute contraindication to transcranial magnetic stimulation, such as having cochlear implant (device to treat deafness) or intracranial metal objects (such as clips for cerebral aneurysm and metal plates); history of seizure in the last 12 months or diagnosis of epilepsy; Treatment with transcranial magnetic stimulation, electroconvulsive therapy or transcranial direct current stimulation in the last 12 months; Alcohol or other drug abuse in the last 06 months; Use of any continuous oral contraceptive (which make the woman do not have menstruation) or containing the substance drospireone ; subcutaneous hormonal implant (implanon); or injectable contraceptives; or intrauterine hormonal device (Mirena IUD);

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome of this study is to achieve a significantly greater reduction in premenstrual symptoms in patients in the experimental group, measured by the score in the Screening Tool for Premenstrual Symptoms for 2 consecutive menstrual cycles.

Secondary Outcome Measures

Name	Time	Method
It is expected to find a more significant reduction in the score obtained in the premenstrual symptoms, recorded in the Daily Registry of Intensity of Problems, in the experimental group, as well as a greater decrease in scores related to depressive and anxious symptoms, and similar rates of adverse effects in both groups. It is also expected to identify possible predictors of favorable response to treatment.