The Effect of Dexmedetomidine and Remifentanil on the Postoperative Sore Throat After Thyroidectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 74
- 试验地点
- 1
- 主要终点
- incidence of postoperative sore throat at rest
研究概览
简要总结
This study was performed to compare the effect on of a postoperative sore throat between dexmedetomidine and remifentanil in patients undergoing thyroidectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who scheduled primary thyroidectomy were enrolled and their physical status was American Society of Anesthesiologists (ASA) class 1 or 2
排除标准
- •Patients with respiratory tract disease, previous head, and neck surgery, preexisting steroid or non-steroidal anti-inflammatory drug use, and known or suspected difficult airway
研究组 & 干预措施
dexmedetomidine infusion group
dexmedetomidine infusion (loading dose of 1 ㎍/kg over 10 min and continuous infusion of 0.3-0.6 ㎍/kg/h) during the surgery
干预措施: dexmedetomidine infusion group (Drug)
remifentanil infusion group
remifentanil of 4 ng/ml during induction, followed by remifentanil infusion (1.5~2.5 ng/ml) during the surgery
干预措施: remifentanil infusion group (Drug)
结局指标
主要结局
incidence of postoperative sore throat at rest
时间窗: 6 hours after surgery
0=none; 1=occur
incidence of postoperative sore throat at swallowing
时间窗: 6 hours after surgery
0=none; 1=occur
severity of postoperative sore throat at rest
时间窗: 6 hours after surgery
4-point scale (0=none; 1=mild; 2=moderate; 3=severe)
severity of postoperative sore throat at swallowing
时间窗: 6 hours after surgery
4-point scale (0=none; 1=mild; 2=moderate; 3=severe)
次要结局
未报告次要终点
研究者
Eun Kyung Choi
Professor
Yeungnam University College of Medicine