The Effect of Dexmedetomidine and Remifentanil Infusion on Postoperative Sore Throat After Lumbar Spine Surgery in the Prone Position
Overview
- Phase
- Not Applicable
- Intervention
- dexmedetomidine infusion
- Conditions
- Post Operative Sore Throat
- Sponsor
- Yeungnam University College of Medicine
- Enrollment
- 104
- Locations
- 1
- Primary Endpoint
- incidence of postoperative sore throat at rest
- Last Updated
- 4 years ago
Overview
Brief Summary
This study was performed to compare the effect of dexmedetomidine and remifentanil on the incidence and severity of postoperative sore throat in patients undergoing spinal surgery in the prone position who are at risk of developing postoperative sore throat.
Investigators
Eun Kyung Choi
Professor
Yeungnam University College of Medicine
Eligibility Criteria
Inclusion Criteria
- •American Society of Anesthesiologists (ASA) physical status classification I and II
- •Undergoing lumbar spine surgery in prone position
Exclusion Criteria
- •Pre-existing sore throat, hoarseness, or upper respiratory tract infection
- •Allergy to the study drugs
- •Anticipated difficult airways
- •More than two attempts at intubation
Arms & Interventions
dexmedetomidine infusion group
dexmedetomidine infusion (loading dose of 1 ㎍/kg over 10 min and continuous infusion of 0.3-0.6 ㎍/kg/h) during the surgery
Intervention: dexmedetomidine infusion
remifentanil infusion group
remifentanil of 0.05 ㎍/kg/h during induction, followed by remifentanil infusion (0.05-0.3 ㎍/kg/h) during the surgery
Intervention: remifentanil infusion
Outcomes
Primary Outcomes
incidence of postoperative sore throat at rest
Time Frame: 1 hour after surgery
0=none; 1=occur
incidence of postoperative sore throat at swallowing
Time Frame: 1 hour after surgery
0=none; 1=occur
severity of postoperative sore throat at rest
Time Frame: 1 hour after surgery
4-point scale (0=none; 1=mild; 2=moderate; 3=severe)
severity of postoperative sore throat at swallowing
Time Frame: 1 hour after surgery
4-point scale (0=none; 1=mild; 2=moderate; 3=severe)