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Clinical Trials/NCT06138574
NCT06138574
Not yet recruiting
Not Applicable

Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital0 sites72 target enrollmentDecember 1, 2023

Overview

Phase
Not Applicable
Intervention
Dexmedetomidine
Conditions
Rhinoplasty Surgery
Sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Enrollment
72
Primary Endpoint
iceb
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

Our aim in this treatment was to reveal the effects of remifentanil and dexmetomidine, which we used to provide controlled hypotension in septorhinoplasty surgery, on cardiac electrophysiology. We planned to compare the patients by recording preoperative and postoperative ECGs. We also planned to record the patients' intraoperative blood pressure, saturation, and pulse rate, rickeragitation scale, and vas score.

Registry
clinicaltrials.gov
Start Date
December 1, 2023
End Date
March 30, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Hülya Tosun Söner

HTosunSoner

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • patients with an ASA score of I and between the ages of 17-45 years, who were to undergo general anesthesia with sevofulurane were included in the study.

Exclusion Criteria

  • Patients aged \<17 and \>45 years, patients with liver and/or kidney failure, obese patients (BMI \>30), trauma patients, ASA II-III-IV patients, patients with bleeding disorders, those using drugs that may affect the coagulation system, patients with cardiomyopathy, cerebrovascular disease, immobility, and malnutrition were excluded from the study.

Arms & Interventions

Effects of Dexmetomidine

Patients in this group will be given dexmedetomidine infusion during the intraoperative period to provide controlled hypotension.

Intervention: Dexmedetomidine

Effects of Remifentanil

Patients in this group will be given remifentanil infusion during the intraoperative period to provide controlled hypotension.

Intervention: Remifentanil

Outcomes

Primary Outcomes

iceb

Time Frame: preoperative and postoperative (immediatly after extubation)

Qt\\Qrs

Secondary Outcomes

  • heart rate(when you come to the operating room table after anesthesia induction Intraoperative 30 minutes after extubasion)
  • Riker Agitation Scale(Immediately after extubation)
  • mean arterial pressure(when you come to the operating room table after anesthesia induction Intraoperative 30 minutes after extubasion)
  • Numeric Rating Scale(Postoperative 0-2 hours)

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