Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 72
- 主要终点
- iceb
研究概览
简要总结
Our aim in this treatment was to reveal the effects of remifentanil and dexmetomidine, which we used to provide controlled hypotension in septorhinoplasty surgery, on cardiac electrophysiology. We planned to compare the patients by recording preoperative and postoperative ECGs. We also planned to record the patients' intraoperative blood pressure, saturation, and pulse rate, rickeragitation scale, and vas score.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 17 Years 至 45 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients with an ASA score of I and between the ages of 17-45 years, who were to undergo general anesthesia with sevofulurane were included in the study.
排除标准
- •Patients aged <17 and >45 years, patients with liver and/or kidney failure, obese patients (BMI >30), trauma patients, ASA II-III-IV patients, patients with bleeding disorders, those using drugs that may affect the coagulation system, patients with cardiomyopathy, cerebrovascular disease, immobility, and malnutrition were excluded from the study.
研究组 & 干预措施
Effects of Dexmetomidine
Patients in this group will be given dexmedetomidine infusion during the intraoperative period to provide controlled hypotension.
干预措施: Dexmedetomidine (Drug)
Effects of Remifentanil
Patients in this group will be given remifentanil infusion during the intraoperative period to provide controlled hypotension.
干预措施: Remifentanil (Drug)
结局指标
主要结局
iceb
时间窗: preoperative and postoperative (immediatly after extubation)
Qt\\Qrs
次要结局
- heart rate(when you come to the operating room table after anesthesia induction Intraoperative 30 minutes after extubasion)
- Riker Agitation Scale(Immediately after extubation)
- mean arterial pressure(when you come to the operating room table after anesthesia induction Intraoperative 30 minutes after extubasion)
- Numeric Rating Scale(Postoperative 0-2 hours)
研究者
Hülya Tosun Söner
HTosunSoner
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital