Bacteriotherapy to Improve Underarm Odor
- Conditions
- Bromhidrosis
- Interventions
- Biological: Bacterial spray
- Registration Number
- NCT03967470
- Lead Sponsor
- University Ghent
- Brief Summary
The goal is to improve the underarm odor by changing the microbiome. The autochthonous bacterial community is replaced by a non-smelling microbiome, by daily application of bacteria in a spray.
- Detailed Description
Participants are recruited and selected based on their initial underarm odor and underarm microbiome. The participants use two sprays: one spray containing the bacteria, and the other nothing (placebo). Participants do not know which spray they have. They use one spray during one month, and meanwhile take samples of their underarm microbiome (for sequencing), volatome (for GC/MS analysis) and odor (for odor panel analysis). Samples are stored in the freezer and brought to the university after one month, when they receive the second spray. The bacterial spray contains bacteria that are correlated with good underarm odor.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 67
- above average underarm malodor
- microbiome dominated with malodorous bacteria
- not healthy
- microbiome with too high levels of Staphylococcus
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Placebo arm Bacterial spray Placebo spray used during one month Treatment arm Bacterial spray Bacteria spray used during one month
- Primary Outcome Measures
Name Time Method Improved underarm odor 1 month Odor panel and GC/MS results provide insights on underarm odor development
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ghent University
🇧🇪Gent, Belgium