Microbial Community Transplantation on the Armpit.

Not Applicable

Completed

• Conditions: Heavy, Bad Odour From Armpit
• Interventions: Biological: Microbial transplant

• Registration Number: NCT01944566
• Lead Sponsor: University Ghent

Brief Summary

The malodour generation of a person's armpit is caused by the bacteria thriving on that armpit. In order to alter or reduce once bad body odour, the living microbial community on the armpit of a non-malodorous person will be transmitted (or up scaled and transmitted) to the armpit of a malodorous person. The odour is evaluated by a trained smelling panel, the bacteria living on the armpit is examined by means of molecular techniques. The microbial transplantation and its follow-up happens under the supervision of a medical doctor.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-09-12
• Study First Submitted QC: 2013-09-12
• Study First Posted: 2013-09-17
• Study Start: 2013-10
• Primary Completion: 2015-06
• Study Completion: 2015-08
• Status Verified: 2021-11
• Last Update Submitted: 2021-11-19
• Last Update Posted: 2021-12-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• bad armpit odour

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
heavy armpit odour	Microbial transplant	subjects with heavy armpit odour

Primary Outcome Measures

Name	Time	Method
Molecular characterisation of the bacterial community after microbial transplantation.	24 evaluations in approximately 10 weeks.	Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis. The measurements take place before (once), during the treatment week (5 times) and after the treatment (2x per week during 2 months).
Reduction of bad odour of the armpit.	24 evaluations in approximately 10 weeks.	Odour evaluation by a trained smelling panel. The measurements take place before (once), during the treatment week (5 times) and after the treatment (2x per week during 2 months).

Secondary Outcome Measures

Name	Time	Method
Reduction of bad odour of the armpit over a longer period.	after 6 months	Odour evaluation by a trained smelling panel.
Molecular characterisation of the bacterial community after microbial transplantation.	After 6 months	Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis.

Trial Locations

Locations (2)

Ghent University Hospital; 🇧🇪 Ghent, Belgium

Ghent University; 🇧🇪 Ghent, Belgium