跳至主要内容
临床试验/NCT03460119
NCT03460119已完成不适用

Use of High-Flow Nasal Cannula for Acute Respiratory Failure in the Emergency Department

Hospital Italiano de Buenos Aires0 个研究点目标入组 43 人开始时间: 2015年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
43
主要终点
Heart Rate

研究概览

简要总结

The aim of this study was to describe the changes in respiratory rate, heart rate and dyspnea, before and after using HFNC in patients presenting to our emergency department with ARF.

详细描述

A retrospective cohort study was performed. To all adults presenting to the emergency department who used high flow nasal cannula to treat clinical signs of acute respiratory failure based on the presence of a breathing frequency ≥ 25 breath/min and increase work of breathing evidence by dyspnea, in-drawing, accessory-muscle use and/or diaphoresis despite conventional oxygen therapy ≥ 6 l/min. Demographic variables and clinical and gasometric parameters before and after two hours using HFNC were recorded.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients aged ≥ 18 years
  • attended between July 1st, 2015 and January 31st , 2017 in the Emergency Department of the Hospital Italiano de Buenos Aires
  • with clinical signs of acute respiratory failure

排除标准

  • Pulse oximetry > 90% breathing room air

结局指标

主要结局

Heart Rate

时间窗: 2 hours

The closest value of Heart Rate before starting HFNC, and two hours later was collected from the electronic clinical history.

Dyspnea

时间窗: 2 hours

The closest value of Dyspnea (Modified Borg Dyspnea scale) before starting HFNC, and two hours later was collected from the electronic clinical history. The Modified Borg Dyspnea Scale is a rated numerical score used to measure dyspnea. This scale has a minimum value of 0 ( represent no dyspnea) and a maximum value of 10 (worse dyspnea).

Respiratory Rate

时间窗: 2 hours

The closest value of Respiratory Rate before starting HFNC, and two hours later was collected from the electronic clinical history.

次要结局

  • Delay of HFNC treatment(until 24hs)
  • Failure of HFNC treatment(28 days)
  • Average time of use the HFNC(until 28 days)
  • Initial HFNC setting(2 hours)
  • Acute respiratory failure etiology(3 minutes)
  • Efficacy of HFNC treatment(28 days)
  • Palliative Care(28 days)
  • Mortality rate at 28 day from ED admission(28 days)

研究者

申办方类型
Other
责任方
Sponsor

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