Optimization of Intraoperative Ventilation Guided by Electrical Impedance Tomography in Combination With Oxygen Saturation by Pulse Oximetry (SpO2) Versus SpO2 Alone in Obese Patients Undergoing Robotic Assisted Radical Prostatectomy: Prospective Randomized Trial

Regina Elena Cancer Institute1 site in 1 country54 target enrollmentFebruary 1, 2021

ConditionsObese

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Obese
Sponsor: Regina Elena Cancer Institute
Enrollment: 54
Locations: 1
Primary Endpoint: The arterial oxygen pressure / fraction of inspired oxygen (pO2 /FiO2) ratio
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The primary objective of our study will be verify a possible improvement in arterial oxygenation in the obese patient undergoing robotic-assisted radical prostatectomy if the ventilation will be guided by electrical impedance tomography rather than peripheral saturation alone.

Registry

clinicaltrials.gov

Start Date

February 1, 2021

End Date

June 1, 2022

Last Updated

5 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Regina Elena Cancer Institute

Responsible Party

Principal Investigator

Ester Forastiere, MD

Head of Department of Anaestesiology and Critical Care

Regina Elena Cancer Institute

Eligibility Criteria

Inclusion Criteria

•Patients scheduled for laparoscopic radical prostatectomy
•BMI ≥ 30 kg/m2

Exclusion Criteria

•surgery duration \< 2 hours
•history of lung diseases

Outcomes

Primary Outcomes

The arterial oxygen pressure / fraction of inspired oxygen (pO2 /FiO2) ratio

Time Frame: 16 months

The primary outcome will be the ratio of arterial oxygen pressure and the fraction of inspired oxygen (pO2 / FiO2 ratio) at the end of the intervention, detected by blood gas analysis.