Evaluation of Immune Response Against the Strain of Neisseria Meningitidis B: 14, P1-7, 16 Patients Have to be Vaccinated MenBVac®
Completed
- Conditions
- Vaccination
- Registration Number
- NCT01054053
- Lead Sponsor
- University Hospital, Rouen
- Brief Summary
The main objective of the study is to estimate the proportion of children, born between the 06/04/2004 and the 17/004/2008, living around Neufchatel en Bray, vaccinated by MenBVac, with a serum bactericidal activity against B:14,P1-7,16 clone related to a protection (\>= 4), before the first vaccination (T0), after the second MenBvac vaccination (6 weeks after the second vaccination), before the third MenBvac vaccination and after the third MenBvac vaccination (6 weeks after the second vaccination) and one year after the third menBvac vaccination.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 218
Inclusion Criteria
- children born between 06/04/2004 and 17/04/2008, living in Neufchatel en Bray, vaccinated five times by MenBVac
- parental authority(ies)assent
Exclusion Criteria
- no parental authority(ies)assent
- no blood sample during the third vaccination
- impossibility of third vaccination
- children with guardianship
- children yet vaccinated or non eligible for vaccination
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method assessment of natural Immunity with measure of percent of children who have hSBA title >= 4 at TO. assessment of antibodies blood persistence during measurement of percent of children who have hSBA title >= 4 18 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Maison Du Département
🇫🇷Neufchâtel En Bray, France