CTRI/2021/06/033985
Completed
未知
Effect of Non Surgical Periodontal therapy in patients with Periodontitis and Type 2 Diabetes Mellitus
Haldia Institute of dental sciences and research0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Sponsor
- Haldia Institute of dental sciences and research
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Subjects with Gingivitis : full mouth bleeding on probing less than 10% of sites.
- •Subjects with Periodontitis : Subjects with Periodontitis with interdental clinical attachment
- •loss detectable at \>\- 2 non adjacent teeth .Buccal or oral clinical attachment loss \>\-3 mm
- •with pocketing \> 3mm is detectable at \>\-2 teeth.
- •Subjects with Periodontally Healthy (PH) : Subjects with PH will have no history of periodontitis, no sites with PD and CAL \> 3 mm concurrently and no more than 10% of the sites with gingival bleeding and/or BoP.
- •Diabetic subjects :The diabetic subjects will require a diagnosis of DM confirmed by a physician, dating from at least 2 years prior to the study. In addition, all diabetic patients will be required to have a HbA1c \> 6\.5% and FPG \> 99 mg/dl.
- •Non\-diabetics: Non\-diabetic subjects will have no history of DM, HbA1c \= 6\.0% and FPG \< 99 mg/dl.
Exclusion Criteria
- •Pregnancy; breastfeeding; subgingival periodontal therapy during the previous 12 months; use of antibiotic, anti\-inflammatory, and/or immunosuppressive therapies during the previous 6 months; regular use of mouthrinses containing antimicrobials; use of orthodontic
- •appliances; presence of other infectious, immunological, and/or inflammatory systemic conditions (e.g., immunological disorders, rheumatoid arthritis) and major complications of DM (i.e.,ulcers, gangrene, amputation, neuropathy, and nephropathy),smokers.
Outcomes
Primary Outcomes
Not specified
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