概览
- 阶段
- 不适用
- 干预措施
- Collection of biological sample (blood and/or CSF)
- 疾病 / 适应症
- Parkinson's Disease; Amyotrophic Lateral Sclerosis; Glioblastoma; Cancer Without Neurological Disease; Rheumatoid Polyarthritis
- 发起方
- Hospices Civils de Lyon
- 入组人数
- 350
- 试验地点
- 1
- 主要终点
- Samples (blood dry and EDTA tube and optional cerebro-spinal-fluid)
- 状态
- 招募中
- 最后更新
- 3个月前
概览
简要总结
Autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS) are rare disease that could be difficult to diagnose. So it necessary to obtain numerous sample from different disease to develop more specific diagnosis kit It could be possible through the characterisation of new genetic biomarkers.
研究者
入排标准
入选标准
- •patient with consent
- •patient with following disease: Parkinson's disease, Amyotrophic lateral sclerosis, Glioblastoma, cancer without neurological disease (pulmonary cancer, breast cancer, ovarian cancer, melanoma, thymoma), rheumatoid arthritis.
排除标准
- •refusal consent
- •patient with neurological disorder compatible with paraneoplastic neurological syndrome or auto-immune encephalitis
- •patient under guardianship
研究组 & 干预措施
Control cohort
Patient with following disease: Parkinson's disease, Amyotrophic lateral sclerosis, Glioblastoma, cancer without neurological disease (pulmonary cancer, breast cancer, ovarian cancer, melanoma, thymoma), rheumatoid arthritis.
干预措施: Collection of biological sample (blood and/or CSF)
结局指标
主要结局
Samples (blood dry and EDTA tube and optional cerebro-spinal-fluid)
时间窗: 15 minutes
Numbers of samples collected and patients included in the cohort
次要结局
- Description of genetic analysis(Data collecting: 3 years Data analysis: 2 years)